WE WANT YOUR (WISDOM) TEETH

https://blog.vib.be/the-woman-and-science-behind-an-incurable-disease

Professor Dr Esther Wolfs from the Biomedical Research Institute (BIOMED) of Hasselt University (Belgium) is looking for wisdom teeth from both patients with CMT1A and HNPP. She is able to convert stem cells from wisdom teeth into Schwann cells. "That is quite unique because few cells suit this purpose. Thanks to this discovery we are now able to imitate the genetic background of the disease. Our initial results look very promising: we can imitate the genetic defect in the Schwann cells."
(Source: https://issuu.com/vubrussel/docs/impactbrochure_eng_def/s/21175664)

You can contact her by email esther.wolfs@uhasselt.be
or by phone (Belgian number): +32 (0)11269296 (https://www.uhasselt.be/nl/wie-is-wie/detail/esther-wolfs). Please contact her BEFORE the extraction so she can contact your surgeon/dentist/orthodontist.

Her department covers for the costs of the transport of the wisdom teeth.

https://today.wayne.edu/medicine/news/2022/01/28/neurologists-get-ready-for-clinical-trial-with-exploratory-grant-worth-2-million-from-nih-46843

2023:  REPOSITIONING OF NIACIN/NIASPANÒ FOR THE THERAPY OF CHARCOT-MARIE-TOOTH NEUROPATHIES WITH FOCAL HYPERMYELINATION
https://iris.unisr.it/handle/20.500.11768/136960: https://hdl.handle.net/20.500.11768/136960 Riposizionamento del farmaco Niaspan (Niacina) per il trattamento di neuropatie Charcot-Marie-Tooth caratterizzate da ipermielinizzazione focale / Silvia Cipriani , 2023 Jan 19. 35. ciclo, Anno Accademico 2021/2022. 

2016: "Here we show that in vivo delivery of Niaspan, a FDA-approved drug known to enhance TACE activity, efficiently rescues myelination in the Mtmr2-/- mouse, a model of CMT4B1 with myelin outfoldings, and in the Pmp22+/- mouse, which reproduces HNPP (hereditary neuropathy with liability to pressure palsies) with tomacula. "
Source: https://pubmed.ncbi.nlm.nih.gov/27799291/: Bolino A, Piguet F, Alberizzi V, Pellegatta M, Rivellini C, Guerrero-Valero M, Noseda R, Brombin C, Nonis A, D'Adamo P, Taveggia C, Previtali SC. Niacin-mediated Tace activation ameliorates CMT neuropathies with focal hypermyelination. EMBO Mol Med. 2016 Dec 1;8(12):1438-1454. doi: 10.15252/emmm.201606349. PMID: 27799291; PMCID: PMC5167133.